Let Thema Put You on a Path to Prevent Cognitive Decline with ApoE Aware, our at-home kit.
How Our Kit Works
Receive your kit
We send you a kit with everything you need to get started including an at-home genetic test
Provide health history
You will receive instructions on how to complete our simple forms that will allow us to better analyze your risk factors
Collect Sample
It is easy to collect your sample at home - a simple cheek swab
Telehealth Consult
Schedule your telehealth consult with one of our neurology providers to go over your results and build a personalized prevention plan
Should I do this?
"Thema Brain Health's team of brain health specialists has developed ApoE Aware, a science-backed at-home genetic test, risk assessment and comprehensive telehealth consultation to deliver a personalized prevention plan. Thema will help you take action today to prevent cognitive decline."
Robert Colton, MD
cofounder & Chairman, Thema Brain Health
founder of MDVIP, the country's largest concierge medicine company
At-Risk Groups
Family History
Do you have a family history of Alzheimer’s Disease or dementia?
If so, it’s important to know your ApoE status.
Women
All women, especially those with greater vasomotor symptoms including hot flashes and brain fog during menopause, are at an increased risk for developing Alzheimer's Disease later in life.
Everyone, especially women approaching menopause age or in menopause should know their ApoE status.
Head Trauma
Repeated concussions are a risk factor for Alzheimer's Disease, especially for those with one or two copies of ApoE 4.
Before participating in a contact sport, you should know your ApoE status.
Taking a Statin
Knowing your ApoE status is important when taking statins because ApoE4 can affect how your body responds to these drugs. ApoE4 carriers might experience an inadequate response to statin therapy.
Memory Complaints
Early memory issues can be a sign of future cognitive decline. Understanding your genetic risk can lead to early intervention.
Metabolic Syndrome
Conditions like diabetes and hypertension can increase Alzheimer's risk. Knowing your ApoE status can guide lifestyle and medical interventions.
There is an epidemic of metabolic syndrome worldwide, due to weight gain, unhealthy diet, and lack of exercise. Patients with metabolic syndrome have triple the risk of AD, the same as carrying ApoE4. If the risk is additive, having one copy of APoE4 and metabolic syndrome would increase your AD risk 6 fold. Knowing your ApoE status might motivate you to approach metabolic disease more aggressively, including intense lifestyle change, and early use of new GLP-1 receptor agonists. These drugs may also have an independent neuroprotective effect.
Not sure how to start? That’s why we developed ApoE Aware.
